High-Risk Drugs Study Guide
The 44-Page A5 High-Risk Drugs Study Guide is a focused, exam-relevant resource designed to help trainee pharmacists understand high-risk drugs. These drugs are frequently tested in the GPhC registration assessment and require strong knowledge of monitoring, interactions, counselling, and safety considerations.
This guide brings together key high-risk medicines in one concise, structured format to support exam preparation and real-world clinical practice.
Topics covered include:
Immunosuppressants and cytotoxics
Azathioprine
Ciclosporin
Methotrexate
Tacrolimus
Diabetes and metabolic medicines
Insulin
Sulphonylureas
SGLT-2 inhibitors
Bone and inflammatory conditions
Bisphosphonates
Aminosalicylates
Cardiovascular and gastrointestinal drugs
Proton pump inhibitors
Antimuscarinics
Reproductive health
Contraception
Antimicrobials requiring close monitoring
Gentamicin
Vancomycin
Teicoplanin
Co-amoxiclav
Quinolones
Ciprofloxacin
High-risk antifungals
Amphotericin B
Itraconazole
Voriconazole
Why this guide?
Written by experienced UK pharmacists
Aligned with BNF, NICE, and GPhC exam expectations
Emphasises monitoring requirements, interactions, contraindications, and counselling points
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